Tag Archives: RNA

Did Study Show Pfizer Vaccine Altering Liver DNA In 6 Hours?!

Did Study Show Pfizer Vaccine Altering Liver DNA In 6 Hours?!

Did a Swedish study show that the Pfizer COVID-19 vaccine altered the DNA of human liver cells in just 6 hours?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Study Show Pfizer Vaccine Altering Liver DNA In 6 Hours!

The Expose is back again, with yet another “fakexpose” on the Pfizer COVID-19 vaccine. This time, they are recycling a February 2022 fake story that I fact checked earlier.

Here are selected excerpts from their long-winded article. Feel free to skip it, and head to the next section for the facts.

A Swedish study has demonstrated and confirmed that the mRNA in the Pfizer/BioNTech Covid injections infiltrates cells and transcribes its message onto human DNA within 6 hours, altering our own DNA.

The findings come after a previous study published in October 2021 from Sweden found the spike protein enters our cells nuclei and impairs the mechanism cells have to repair damaged DNA.

Read more : Did 800 People Quit Pfizer Vaccine Trial Over Death / Injury?!

 

Truth : Study Did Not Show Pfizer Vaccine Altering Liver DNA In 6 Hours

This is yet another example of vaccine fake news based on the intentional misinterpretation of a single scientific study.

Here is what you really need to know about this Lund University study… and The Expose.

Fact #1 : The Expose Is A Fake News Website

The Expose is notorious for creating and propagating fake news on everything from COVID-19 to vaccines and the Ukraine war.

I investigated several articles they wrote, and they were all found to be completely false, or intentionally misleading.

Everything posted by The Expose must be considered fake news, until proven otherwise.

Fact #2 : Study Did NOT Say Pfizer Vaccine Alters Our DNA

First things first – the Lund University study is called Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, and you can read it in its entirety here.

If you read just the discussion, you will note that the study authors actually pointed out that their study does NOT show that the Pfizer vaccine integrates with the liver cell DNA, or alters it in any way.

At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome.

To be clear, the study offers no evidence that the Pfizer COVID-19 vaccine alters our DNA in any way or form.

Fact #3 : It Was A Laboratory Study

I should also point out the obvious fact that this was an in-vitro study – a laboratory study, not a clinical study.

In-vitro studies are important, but they cannot be extrapolated to make any conclusion about what actually happens in a human body.

For example, in-vitro studies have shown that hydroxychloroquine and ivermectin have an inhibitory effect on the SARS-CoV-2 virus; but once tested in actual human beings – they were shown to have no clinical benefit.

In other words – what works in a laboratory, may not work in an actual human being.

Read more : Study Shows 10X Ivermectin Can’t Prevent Severe COVID-19!

Fact #4 : Study Was Based On Liver Cancer Cells

The casual reader of the Lund University study will not realise that Huh7 (or Huh-7) cells are not ordinary liver cells that you or I have.

Huh7 cells were derived from the liver tumour of a 57 year-old Japanese man, and are special because :

  • they are immortal liver cancer cells that can keep multiplying
  • they are highly-susceptible to Hepatitis C virus (HCV) infection
  • they are genetically different, with an abnormal number of chromosomes (between 55 and 63, normal human cells have 46)

The Huh7 cell line is useful for the study of liver cancer and Hepatitis C, as well as drugs that may combat HCV; but it is important to understand that Huh7 cells are not representative of normal human cells.

Fact #5 : Huh7 Liver Cells Were Cultured In Plates

For a “more physiologically relevant study of viruses“, these Huh7 cells have to be cultured in a NASA-designed 3D Rotating Wall Vessel (RWV) bioreactor.

These RWV bioreactors create 3D aggregates of Huh7 cells that are more “similar in structure and function” to their in vivo counterparts, with “completely altered gene expression and differentiation patterns“.

In other words, these RWV-grown Huh7 cells look and behave differently, more like regular human cells compared to plate-cultured Huh7 cells.

For the record, the Lund University study used plate-cultured Huh7 cells, and not RWV-grown Huh7 cells.

There is nothing wrong with that, but we should keep in mind that these cells are not an ideal representation of human cells.

This is what a 24-cell culture plate looks like

Fact #6 : Normal Human Cells Don’t Produce LINE-1 Enzyme

The scientists chose to use these Huh7 cells because like many cancerous cells, they express (produce) the LINE-1 enzyme.

LINE-1 is a reverse transcriptase that converts mRNA into DNA, so it is not surprising that the study would show it converting mRNA from the Pfizer COVID-19 vaccine into DNA. That is literally what it is meant to do.

Normal human cells have the LINE-1 gene, but it is not expressed. Normal human cells do not produce the LINE-1 enzyme, which is why they could not use regular human cells in this study.

That is also why it is inappropriate to use the Huh7 cell culture to evaluate how mRNA vaccines would actually work or behave in humans.

Fact #7 : Transcribed DNA Did Not Enter Nucleus

The study only looked at whether mRNA from the Pfizer COVID-19 vaccine can be transcribed into DNA by the LINE-1 enzyme.

As the study showed – yes, it can… because that’s what the LINE-1 enzyme does. But the study does not show that the transcribed DNA entered the cell nucleus and altered human DNA.

While that is plausible, it would require another enzyme called integrase, that viruses produce, to move that DNA into the cell nucleus itself.

Without the integrase enzyme, the DNA transcribed by the LINE-1 enzyme will only float outside, and will never integrate with the DNA inside the cell nucleus.

Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Fact #8 : mRNA Vaccines Do Not Modify Our Genes

An mRNA vaccine only contains a limited number of lipid nanoparticles containing those delicate mRNA instructions. So only a limited number of cells are involved in the vaccination process.

Even if it is somehow possible for the mRNA instructions from the vaccine to enter the cell nucleus and integrate with the DNA inside, it will only affect those cells.

Our cells die and are replaced by new cells all the time, so even if hypothetically the vaccine “infects” and modifies the DNA of a few hundred thousand cells, those cells will eventually die and be replaced by new cells without the modified DNA.

It is simply not possible for mRNA vaccines to modify our genes.

Fact #9 : Viruses Integrate With Cell DNA

Viruses like SARS-CoV-2 and HIV-1 (diagram below) integrate their genes with the host cell DNA, to hijack the cell and use it to produce copies of itself.

You can see how a typical RNA virus would infect a host cell, convert its RNA into DNA which is moved into the cell nucleus using the integrase enzyme.

HIV-1 virus cell infection, credit : Günther Witzany

Once inside, the viral DNA integrates with the host cell DNA, which gets transcribed into instructions for the cell to produce copies of the virus.

This is the same way how the SARS-CoV-2 virus infects our cells, to produce copies of itself to infect even more cells.

If you are truly worried about anything modifying your cell’s DNA, you should try to avoid viral infections like COVID-19. Better still – vaccinate yourself, and get protected against COVID-19!

Everything posted by The Expose must be regarded as FAKE NEWS, until proven otherwise.

Please help us FIGHT FAKE NEWS by sharing this article out, and supporting our work!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

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Was Pfizer COVID-19 Vaccine Proven To Change Our DNA?!

Did Swedish scientists just prove that the Pfizer COVID-19 vaccine changes our DNA?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Pfizer COVID-19 Vaccine Changes Our DNA!

Anti-vaccination and ivermectin proponents have gone bananas over the new study from the Lund University in Sweden.

They are sharing it as evidence (finally!) of the Pfizer COVIDS-19 vaccine actually integrating with our DNA, and changing our genome, as they had always claimed.

Let that shock and horror sink in for a minute… and then let me explain to you what the facts really are in the next section…

 

Truth : Pfizer COVID-19 Vaccine Did NOT Change DNA At All!

This is yet another example of vaccine fake news based on accidental / intentional misinterpretation of a single scientific study.

Here is what you really need to know about the Lund University study that went viral…

Fact #1 : Study Did NOT Say Pfizer Vaccine Alters Our DNA

First things first – the Lund University study is called Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, and you can read it in its entirety here.

In the study’s Discussion section, the authors actually pointed out that their study does NOT show that the Pfizer vaccine integrates with the liver cell DNA, or alters it in any way.

At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome.

To be clear, the study does NOT show that the Pfizer COVID-19 vaccine changes our DNA in any way or form.

Fact #2 : It Was A Laboratory Study

I should also point out the salient fact that it was an in-vitro study – a laboratory study, not a clinical study.

In-vitro studies are important, but they cannot be extrapolated to make any conclusion about what actually happens in a human body.

For example, laboratory studies do show that hydroxychloroquine and ivermectin have an inhibitory effect on the SARS-CoV-2 virus; but once tested in actual human beings – they are shown to have no clinical benefit.

In other words – what works in a laboratory, may not work in an actual human being.

Read more : Study Shows 10X Ivermectin Can’t Prevent Severe COVID-19!

Fact #3 : Study Was Based On Liver Cancer Cells

The casual reader of the Lund University study will not realise that Huh7 (or Huh-7) cells are not ordinary liver cells that you or I have.

Huh7 cells were derived from the liver tumour of a 57 year-old Japanese man, and are special because :

  • they are immortal liver cancer cells that can keep multiplying
  • they are highly-susceptible to Hepatitis C virus (HCV) infection
  • they are genetically different, with an abnormal number of chromosomes (between 55 and 63, normal human cells have 46)

The Huh7 cell line is useful for the study of liver cancer and Hepatitis C, as well as drugs that may combat HCV; but it is important to understand that Huh7 cells are not representative of normal human cells.

Fact #4 : Huh7 Liver Cells Were Cultured In Plates

For a “more physiologically relevant study of viruses“, these Huh7 cells have to be cultured in a NASA-designed 3D Rotating Wall Vessel (RWV) bioreactor.

These RWV bioreactors create 3D aggregates of Huh7 cells that are more “similar in structure and function” to their in vivo counterparts, with “completely altered gene expression and differentiation patterns“.

In other words, these RWV-grown Huh7 cells look and behave differently, more like regular human cells compared to plate-cultured Huh7 cells.

For the record, the Lund University study used plate-cultured Huh7 cells, and not RWV-grown Huh7 cells.

There is nothing wrong with that, but we should keep in mind that these cells are not an ideal representation of human cells.

This is what a 24-cell culture plate looks like

Fact #5 : Normal Human Cells Don’t Produce LINE-1 Enzyme

The scientists chose to use these Huh7 cells because like many cancerous cells, they express (produce) the LINE-1 enzyme.

LINE-1 is a reverse transcriptase that converts mRNA into DNA, so it is not surprising that the study would show it converting mRNA from the Pfizer COVID-19 vaccine into DNA. That is literally what it is meant to do.

Normal human cells have the LINE-1 gene, but it is not expressed. Normal human cells do not produce the LINE-1 enzyme, which is why they could not use regular human cells in this study.

That is also why it is inappropriate to use the Huh7 cell culture to evaluate how mRNA vaccines would actually work or behave in humans.

Fact #6 : Transcribed DNA Did Not Enter Nucleus

The study only looked at whether mRNA from the Pfizer COVID-19 vaccine can be transcribed into DNA by the LINE-1 enzyme.

As the study showed – yes, it can… because that’s what the LINE-1 enzyme does. But the study does not show that the transcribed DNA entered the cell nucleus and changed human DNA.

While that is plausible, it would require another enzyme called integrase, that viruses produce, to move that DNA into the cell nucleus itself.

Without the integrase enzyme, the DNA transcribed by the LINE-1 enzyme will only float outside, and will never integrate with the DNA inside the cell nucleus.

Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Fact #7 : mRNA Vaccines Do Not Modify Our Genes

An mRNA vaccine only contains a limited number of lipid nanoparticles containing those delicate mRNA instructions. So only a limited number of cells are involved in the vaccination process.

Even if it is somehow possible for the mRNA instructions from the vaccine to enter the cell nucleus and integrate with the DNA inside, it will only affect those cells.

Our cells die and are replaced by new cells all the time, so even if hypothetically the vaccine “infects” and modifies the DNA of a few hundred thousand cells, those cells will eventually die and be replaced by new cells without the modified DNA.

It is simply not possible for mRNA vaccines to modify our genes.

Fact #8 : Viruses Integrate With Cell DNA

Viruses like SARS-CoV-2 and HIV-1 (diagram below) integrate their genes with the host cell DNA, to hijack the cell and use it to produce copies of itself.

You can see how a typical RNA virus would infect a host cell, convert its RNA into DNA which is moved into the cell nucleus using the integrase enzyme.

HIV-1 virus cell infection, credit : Günther Witzany

Once inside, the viral DNA integrates with the host cell DNA, which gets transcribed into instructions for the cell to produce copies of the virus.

This is the same way how the SARS-CoV-2 virus infects our cells, to produce copies of itself to infect even more cells.

If you are truly worried about anything modifying your cell’s DNA, you should try to avoid viral infections like COVID-19. Better still – vaccinate yourself, and get protected against COVID-19!

Now that you know the truth, please help us fight fake news by SHARING this article out!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Health | Fact Check | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Why MAECC Is Wrong About Pfizer mRNA Vaccine Study!

The MAECC is at it again, calling for a pause on the COVID-19 vaccine mandate because of a recent Swedish study on the Pfizer mRNA vaccine!

Let’s take a look at their claims, and find out what the facts really are!

 

MAECC : Pause Vaccine Mandate Over Pfizer mRNA Vaccine Study!

The MAECC (Malaysian Alliance for Effective Covid Control) has issued yet another call for the Malaysia Health Ministry to pause the “vaccine mandate”.

This time, they are using the recently-released Swedish study that allegedly shows the Pfizer mRNA vaccine being converted into DNA.

Their press release is very long, so feel free to skip it and head over to the next section for the facts.

PAUSE ON VACCINE MANDATE IS NECESSARY ON LATEST SCIENTIFIC FINDING

Malaysian Alliance for Effective Covid Control (MAECC) would like to highlight a recently published study that has confirmed the messenger RNA (mRNA) from the Pfizer Covid vaccine is able to enter human liver cells and convert into DNA. From the outset MAECC has been very concerned for the potential long-term adverse effect of the mRNA Covid vaccine, and this includes DNA change. Our fear is now confirmed.

 

Here’s Why MAECC Is Wrong About Pfizer mRNA Vaccine Study!

The MAECC has stridently promoted ivermectin, despite the lack of evidence, and came out strongly against vaccination even though COVID-19 vaccines have been proven to be safe and effective.

Here are the reasons why they are, yet again, wrong about the Pfizer mRNA COVID-19 vaccine.

Fact #1 : There Is No Vaccine Mandate In Malaysia

First, let me address their title – there is no COVID-19 vaccine mandate in Malaysia.

No one is forced to take the COVID-19 vaccine in Malaysia. Any claim that there is a COVID-19 vaccine mandate is undeniably false.

Heck, Malaysia has no vaccine mandate, period. That’s why children of antivax parents remain unvaccinated, despite the risks to their health.

If they start off with a factually false title, what hope is there that their press release is actually based on facts?

Fact #2 : Swedish Study Did Not Show Pfizer Vaccine Changed DNA

The crux of their new press release is the recently-released Pfizer mRNA vaccine study by the Lund University of Sweden.

The MAECC claimed that their fear that the mRNA vaccine can change our DNA “is now confirmed“. That’s nonsense.

The Swedish researchers themselves pointed out in their study, that :

At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome.

To be clear, the study does not show that the Pfizer mRNA vaccine altered our DNA in any way or form.

The study does not even show that the transcribed DNA entered the cell nucleus!

Read more : Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Fact #3 : Study Findings Did Not Shock Scientists / Physicians

The MAECC claims that the Swedish study findings has “shocked scientists and physicians throughout the world“. That is utter nonsense, unless they mean the few who did not read the study, or actually understand what it stated.

You don’t see health authorities ordering the immediate cessation or pause of mRNA vaccination, as some have done when some real adverse effect was discovered, like the risk of pericarditis / myocarditis.

Instead, the only people calling for mRNA vaccines to be stopped based on this laboratory study are fringe groups like the MAECC.

That’s because everyone else spent their time reading and understanding what the study meant, instead of “accidentally” or intentionally misinterpreting its results to push their own agenda.

If you are interested to know more about what the results of this Swedish study actually mean, please read my article – Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Fact #4 : Waning Immunity Is Indirect Evidence Of No DNA Change

The waning immunity of COVID-19 vaccines is actually indirect evidence that mRNA vaccines do NOT change our DNA. Here’s why…

mRNA vaccines work by instructing some of our cells to manufacture the SARS-CoV-2 virus spike proteins, and put them on the cell surface to trigger the immune system into action.

If the mRNA vaccine actually integrates into our human DNA, all of our cells would display those spikes and continuously trigger the immune system for lifetime protection. That is not simply not the case.

In fact, it is now known that our COVID-19 antibody levels gradually drop after we are fully-vaccinated, which is why a booster dose is required to boost antibody levels after a few months.

Booster doses would not be necessary if the mRNA vaccine actually integrates with our DNA, making all our cells produce the SARS-CoV-2 spike protein forever.

Read more : Sinovac Vaccine Efficacy Rapidly Drops After 2 Months!

Fact #5 : mRNA Vaccine Proven Safe + Effective

MAECC claims that bad science is “behind the promotion and coercion of the masses to get the injections“. That’s utter nonsense. They are the ones propagating bad science.

COVID-19 vaccines have undergone the world’s largest clinical trials, collectively involving over hundreds of thousands of volunteers – far more than clinical trials of vaccines and drugs in the past!

All those clinical trials have shown that the approved COVID-19 vaccines are all safe and effective. Even then, these vaccines continue to be monitored for safety issues.

Over 10 billion doses of COVID-19 vaccines have been administered worldwide, and we are already able to confirm rare adverse effects like anaphylaxis and myocarditis with mRNA vaccines.

If it’s true that mRNA vaccines are able to modify our DNA, we would have seen those effects in the real world, not only in a small laboratory study of liver cancer cells.

Don’t risk your life or your family’s lives on the bad science and misinformation promoted by fringe groups like the MAECC.

Please help me fight fake news, by sharing this fact check with your family and friends!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Health | Fact Check | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Did scientists prove that the Pfizer mRNA vaccine combined with the DNA of liver cells?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Pfizer mRNA Vaccine Combined With DNA In Liver Cells!

Anti-vaccination and ivermectin proponents have gone bananas over the new study from the Lund University in Sweden.

They are sharing it as evidence (finally!) of the Pfizer mRNA vaccine actually integrating with our DNA, and changing our genome, as they had always claimed.

Let that shock and horror sink in for a minute… and then let me explain to you what the facts really are in the next section…

 

Truth : Pfizer mRNA Vaccine Did NOT Combine With DNA In Liver Cells!

This is yet another example of vaccine fake news based on accidental / intentional misinterpretation of a single scientific study.

Here is what you really need to know about this Lund University study…

Fact #1 : Study Did NOT Say Pfizer Vaccine Alters Our DNA

First things first – the Lund University study is called Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, and you can read it in its entirety here.

If you read just the discussion, you will note that the study authors actually pointed out that their study does NOT show that the Pfizer vaccine integrates with the liver cell DNA, or alters it in any way.

At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome.

To be clear, the study offers no evidence that the Pfizer COVID-19 vaccine alters our DNA in any way or form.

Fact #2 : It Was A Laboratory Study

I should also point out the obvious fact that this was an in-vitro study – a laboratory study, not a clinical study.

In-vitro studies are important, but they cannot be extrapolated to make any conclusion about what actually happens in a human body.

For example, in-vitro studies have shown that hydroxychloroquine and ivermectin have an inhibitory effect on the SARS-CoV-2 virus; but once tested in actual human beings – they are shown to have no clinical benefit.

In other words – what works in a laboratory, may not work in an actual human being.

Read more : Study Shows 10X Ivermectin Can’t Prevent Severe COVID-19!

Fact #3 : Study Was Based On Liver Cancer Cells

The casual reader of the Lund University study will not realise that Huh7 (or Huh-7) cells are not ordinary liver cells that you or I have.

Huh7 cells were derived from the liver tumour of a 57 year-old Japanese man, and are special because :

  • they are immortal liver cancer cells that can keep multiplying
  • they are highly-susceptible to Hepatitis C virus (HCV) infection
  • they are genetically different, with an abnormal number of chromosomes (between 55 and 63, normal human cells have 46)

The Huh7 cell line is useful for the study of liver cancer and Hepatitis C, as well as drugs that may combat HCV; but it is important to understand that Huh7 cells are not representative of normal human cells.

Fact #4 : Huh7 Liver Cells Were Cultured In Plates

For a “more physiologically relevant study of viruses“, these Huh7 cells have to be cultured in a NASA-designed 3D Rotating Wall Vessel (RWV) bioreactor.

These RWV bioreactors create 3D aggregates of Huh7 cells that are more “similar in structure and function” to their in vivo counterparts, with “completely altered gene expression and differentiation patterns“.

In other words, these RWV-grown Huh7 cells look and behave differently, more like regular human cells compared to plate-cultured Huh7 cells.

For the record, the Lund University study used plate-cultured Huh7 cells, and not RWV-grown Huh7 cells.

There is nothing wrong with that, but we should keep in mind that these cells are not an ideal representation of human cells.

This is what a 24-cell culture plate looks like

Fact #5 : Normal Human Cells Don’t Produce LINE-1 Enzyme

The scientists chose to use these Huh7 cells because like many cancerous cells, they express (produce) the LINE-1 enzyme.

LINE-1 is a reverse transcriptase that converts mRNA into DNA, so it is not surprising that the study would show it converting mRNA from the Pfizer COVID-19 vaccine into DNA. That is literally what it is meant to do.

Normal human cells have the LINE-1 gene, but it is not expressed. Normal human cells do not produce the LINE-1 enzyme, which is why they could not use regular human cells in this study.

That is also why it is inappropriate to use the Huh7 cell culture to evaluate how mRNA vaccines would actually work or behave in humans.

Fact #6 : Transcribed DNA Did Not Enter Nucleus

The study only looked at whether mRNA from the Pfizer COVID-19 vaccine can be transcribed into DNA by the LINE-1 enzyme.

As the study showed – yes, it can… because that’s what the LINE-1 enzyme does. But the study does not show that the transcribed DNA entered the cell nucleus and altered human DNA.

While that is plausible, it would require another enzyme called integrase, that viruses produce, to move that DNA into the cell nucleus itself.

Without the integrase enzyme, the DNA transcribed by the LINE-1 enzyme will only float outside, and will never integrate with the DNA inside the cell nucleus.

Did Pfizer mRNA Vaccine Combine With DNA In Liver Cells?!

Fact #7 : mRNA Vaccines Do Not Modify Our Genes

An mRNA vaccine only contains a limited number of lipid nanoparticles containing those delicate mRNA instructions. So only a limited number of cells are involved in the vaccination process.

Even if it is somehow possible for the mRNA instructions from the vaccine to enter the cell nucleus and integrate with the DNA inside, it will only affect those cells.

Our cells die and are replaced by new cells all the time, so even if hypothetically the vaccine “infects” and modifies the DNA of a few hundred thousand cells, those cells will eventually die and be replaced by new cells without the modified DNA.

It is simply not possible for mRNA vaccines to modify our genes.

Fact #8 : Viruses Integrate With Cell DNA

Viruses like SARS-CoV-2 and HIV-1 (diagram below) integrate their genes with the host cell DNA, to hijack the cell and use it to produce copies of itself.

You can see how a typical RNA virus would infect a host cell, convert its RNA into DNA which is moved into the cell nucleus using the integrase enzyme.

HIV-1 virus cell infection, credit : Günther Witzany

Once inside, the viral DNA integrates with the host cell DNA, which gets transcribed into instructions for the cell to produce copies of the virus.

This is the same way how the SARS-CoV-2 virus infects our cells, to produce copies of itself to infect even more cells.

If you are truly worried about anything modifying your cell’s DNA, you should try to avoid viral infections like COVID-19. Better still – vaccinate yourself, and get protected against COVID-19!

Now that you know the truth, please help us fight fake news by SHARING this article out!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Health | Fact Check | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

COVID-19 Rapid Tests : What You Need To Know!

Scientists are racing to develop COVID-19 rapid tests, which promise not only to be much cheaper, but also much faster, delivering results in a fraction of the time.

You may have seen some of them for sale too. Are any of these COVID-19 rapid tests the real deal? Let’s find out…

 

COVID-19 Laboratory Tests : How Do They Work?

Laboratory testing for COVID-19, as per WHO recommendations, are Nucleic Acid Amplification Tests (NAAT) using real-time reverse transcription polymerase chain reaction (rRT-PCR)

They basically use RNA primers to target and cut specific segments of COVID-19 genes, so they can be amplified and then identified by RNA / DNA probes.

Different countries may look for different gene targets :

Country Institute Gene targets
China China CDC ORF1ab and N
Germany Charité RdRP, E, N
Hong Kong SAR HKU ORF1b-nsp14, N
Japan National Institute of Infectious Diseases, Department of Virology III Pancorona and multiple targets, Spike protein
Thailand National Institute of Health N
US US CDC Three targets in N gene
France Institut Pasteur, Paris Two targets in RdRP

Such laboratory tests usually take less than 24 hours to complete, although backlog of tests may result in longer wait times.

 

COVID-19 Rapid Tests : How Do They Work?

COVID-19 rapid tests cut down time and costs by avoiding the need for the cutting and amplification of nucleic acid samples.

Instead of looking for specific viral genes, these rapid tests look for IgM – the first antibodies our body makes to fight a new infection. Some rapid tests also look for IgG – the most abundant antibodies in the body.

That’s why they use blood samples, instead of nasopharyngeal swab (NP) or oropharyngeal swab (OP).

Credit : MBL Life Science Japan

To “fish” for COVID-19 specific IgM and/or IgG antibodies, these rapid test kits use selected parts of the COVID-19 capsule proteins as antigens – bait – which are combined with colloidal gold as a marker.

When you drop a blood sample, COVID-19 antibodies (if present in the blood) will be “attracted” to the “bait” – the COVID-19 capsule proteins in the rapid test.

The antibodies will combine with the antigens, forming a visible, coloured compound which will appear as a red / burgundy line in the test strip.

 

COVID-19 Rapid Tests : What’s Available?

Now, there is no doubt that we will come up with COVID-19 rapid tests. It is what scientists are frantically working on. Look at how many have already been created :

Some are already available for sale online :

They are certainly cheap – much cheaper than private COVID-19 testing available to those who are currently deemed not at risk.

 

COVID-19 Rapid Tests : Should You Use Them?

Now, these tests are no doubt convenient – allowing you to do it at home – and cheap. However, are they accurate and ready for use at home, by the public who are not trained in taking blood samples?

While health authorities are eager for such fast and cheap testing options, they are currently NOT advising people to use these COVID-19 rapid tests.

There will come a time when these COVID-19 rapid test kits are properly tested, and approved for use at home. Until then, it’s best to stay away…

Public Health England

Some manufacturers are selling products for the diagnosis of COVID-19 infection in community settings, such as pharmacies.

The current view by PHE is that use of these products is not advised:

  • some of these products look for virus while others look for the body’s immune response to the virus. Such tests are very rapid and can work on a range of specimens including serum, plasma or finger-prick whole blood
  • there is little information on the accuracy of the tests, or on how a patient’s antibody response develops or changes during COVID-19 infection. It is not known whether either a positive or negative result is reliable
  • currently there is no published evidence about the suitability of these tests for diagnosing COVID-19 infection in a community setting

Peter White, UNSW Virologist

The tests are not always as reliable as those currently being used. Because rapid test kits look for antibodies associated with the virus rather than the virus itself, they could record false negatives if used at the wrong time.

The question is how significant those limitations are. It depends really on how many true cases you detect. Does it detect every positive, or does it miss 5%?

Bill Bowtell, Infectious Disease Expert, Kirby Institute

In the end, anybody with anything to sell is in the market and their interest is to make the biggest claims.

I think that’s the case with a lot of the things that we’ll see coming onto the market. There’s uncertainty because it didn’t come to market after stringent testing, it came to the market because there’s a feeling of ‘my god we need it’.

In normal circumstances you wouldn’t touch it with a barge pole but this is what happens when there’s a crisis.

It is also notable that, as of 9 March 2020, China denied that they approved any COVID-19 test kits for use by the public at home :

The Beijing Medical Products Administration denied rumors that claimed that people can test for the novel coronavirus using a home testing kit and added there was no authorized home version of the test yet.

A so-called home testing kit went viral on WeChat, with the seller claiming the result would be visible 15 minutes after adding a drop of blood from one’s finger to the kit. The product was recommended for office buildings and schools to test those returning and isolated at home who could not access a medical test at the hospital.

According to the administration, samples carried by authorized testing kits can only be tested in polymerase chain reaction (PCR) laboratories or other medical institutes. There is no self-testing device yet and those sold on WeChat are fake.

 

COVID-19 : How To Keep Safe!

Here are a few simple steps to stay safe from COVID-19 :

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  • Avoid suspected cases or disease hotpots, like hospitals, if possible!
  • Avoid public events and crowds
  • Keep our hands clean with soap or hand sanitiser
  • Keep our home, office, vehicles, etc. clean
  • If you need to wear a surgical mask, make sure you put it on and remove it properly!
  • Thoroughly cook your food, and boil water before drinking

Recommended : Soap vs Sanitiser : Which Works Better Against COVID-19?
Recommended : Surgical Mask : How To CORRECTLY Wear + Remove!

 

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