Tag Archives: Johnson & Johnson

Malaysia : Sinopharm + Janssen Vaccines Approved!

Malaysia : Sinopharm + Janssen Vaccines Approved!

Malaysia has conditionally approved the Sinopharm and Janssen COVID-19 vaccines!

Find out this means for the COVID-19 vaccination program in Malaysia!

 

Malaysia Approves Sinopharm + Janssen COVID-19 Vaccines!

On 16 July 2021, the Malaysia Ministry of Health announced that the Drug Control Authority (DCA) issued a conditional registration for the following vaccines :

  1. COVILO Suspension for Injection COVID-19 Vaccine (Vero Cell), Inactivated
    Registrant : Duopharma (M) Sdn. Bhd.
    Manufacturer : Beijing Institute of Biological Products Co. Ltd. (BIBP), China
    COVILO is also known as Sinopharm COVID-19 vaccine, and was developed by China National Biotec Group Company Limited (CNBG), also known as Sinopharm
  2. Janssen COVID-19 Vaccine Suspension for Injection
    Registrant : Johnson & Johnson Sdn. Bhd.
    Manufacturer : Janssen Pharmaceutica N.V., Belgium

This conditional registration allows both COVID-19 vaccines to be used in the Malaysia COVID-19 vaccination program.

 

Sinopharm + Janssen Vaccines : A Quick Primer!

The Sinopharm COVILO vaccine, also known as BBIBP-CorV or just BIBP, that is very similar to the CoronaVac vaccine made by Sinovac.

Like CoronaVac, COVILO is an inactivated virus vaccine made from actual SARS-CoV-2 virus grown in Vero cells, and killed using β-propiolactone.

Once injected into the body, the antigens on the inactivated SARS-CoV-2 virus triggers the body’s immune system. It is a two-shot vaccine with an efficacy of :

  • 79% against symptomatic COVID-19.
  • 79% against hospitalisation with COVID-19

The Janssen vaccine from Johnson & Johnson is a viral-vector vaccine that uses the same Ad26 adenovirus as the Russian Sputnik V vaccine.

Once injected into the body, the Ad26 virus teaches some of our cells to manufacture the SARS-CoV-2 protein spikes to trigger the body’s immune system.

The Janssen vaccine is a single-shot vaccine with an efficacy of :

  • 52% to 74% against mild to moderate COVID-19.
  • 73% to 82% against severe to critical COVID-19

 

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Malaysia Approves CanSino + J&J COVID-19 Vaccines!

KKM has conditionally approved the CanSino and Johnson & Johnson COVID-19 vaccines for use in Malaysia!

Find out what this means for the COVID-19 vaccination programme in Malaysia!

 

Malaysia Approves CanSino + J&J COVID-19 Vaccines!

On 15 June 2021, the Malaysia Ministry of Health (KKM) announced that both the CanSino and Johnson & Johnson vaccines against COVID1-9 received conditional approval :

  1. Convidecia Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
    Registrant : Solution Biologics Sdn. Bhd.
    Manufacturer : CanSino Biologics Inc, China
  2. Janssen COVID-19 Vaccine
    Registrant : None (under COVAX Facility)
    Manufacturer : NA

Interestingly, both of these are single dose vaccines, which should make for easier and faster COVID-19 vaccinations.

 

CanSino + J&J COVID-19 Vaccines : A Quick Primer

The CanSino Convidecia vaccine works similarly to other viral vector vaccines, like the AstraZeneca AZD1222 and Gamaleya Sputnik V vaccines.

It uses a modified Ad5 virus containing the DNA instructions for the SARS-CoV-2 protein spike, which are then created by your own cells and presented on their surfaces.

These “foreign” protein spikes triggers the body’s immune system, which then makes antigens to target these spikes.

Recommended : CanSino COVID-19 Vaccine : What You Need To Know!

The Johnson & Johnson Janssen COVID-19 vaccine is similar to the CanSino Convidecia vaccine, except it uses a modified Ad26 virus to carry the DNA instructions for the SARS-CoV-2 protein spike.

Once injected, the DNA instructions are used to manufacture the SARS-CoV-2 spike protein, which is presented on the cell surface to trigger our immune system.

The antibodies they create will attack the real SARS-CoV-2 virus, which would prevent or mitigate an infection.

 

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Which COVID-19 Vaccine Should YOU Choose?

Now that there are several COVID-19 vaccine options, people are demanding for the right to choose.

But should you be given the option to choose, which COVID-19 vaccine should you choose?

2021-04-13 : Updated with new information.

Originally posted @ 2021-03-02

 

COVID-19 Vaccine : So Many To Choose From?

Several COVID-19 vaccine candidates successfully completed their Phase 3 trials, and have received EUA (Emergency Use Authorisation) from various countries.

Company Brand Name Other Name EUA Full
Pfizer-BioNTech Comirnaty BNT162b2 101 5
Oxford-AstraZeneca AZD1222 101 1
Gamaleya Research
Institute
Sputnik V Gam-COVID-Vac 60 3
Moderna mRNA-1273 40 2
Johnson & Johnson Janssen COVID-19 Ad26.COV2.S 40 0
Sinopharm BBIBP-CorV 38 4
Sinovac Biotech CoronaVac 27 1
CanSino Biologics Convidecia Ad5-nCoV 5 1

Many countries ordered several vaccine candidates at the same time, because a single vaccine manufacturer cannot possibly provide enough vaccines to cover an entire population.

Malaysia, for instance, purchased five COVID-19 vaccine candidates :

However, with multiple COVID-19 vaccine types being deployed, it has given people the idea that they should have the right to pick and choose the vaccine.

So which should YOU choose?

 

COVID-19 Vaccine : Which Should YOU Choose?

Most countries will provide the COVID-19 vaccines FREE of charge, but the type of vaccine used will depend on what’s available – you are NOT allowed to pick and choose.

Even so, many people are demanding the right to pick and choose their COVID-19 vaccine. Some are demanding the right to pay for what they believe are the ‘superior’ vaccine.

But guess what…

The BEST vaccine you can take is the FIRST vaccine you can get, and COMPLETE.

Here are the reasons why…

Reason #1 : Early Protection Offers The Best Protection

Think of the COVID-19 pandemic as an alien invasion, and the vaccine as body armour that protects you against their attacks.

When you are under attack, do you put on the first body armour you find, or do you wait until you find the body armour you like the best?

Cpl. Daniel M. Greenwald survived this sniper shot thanks to his helmet!

The fact is – even “substandard” body armour will offer you FAR MORE protection than no body armour at all!

After all, you could end up getting killed by COVID-19, before your preferred body armour arrives. What’s the point of getting the vaccine you want if you are already infected or dead?

Don’t believe us? A team of scientists actually did a study on this, concluding that “waiting for a vaccine with a higher efficacy results in additional hospitalizations and costs over the course of the pandemic“.

Reason #2 : All Approved Vaccines Protect You Against Severe Disease + Death

Regulatory bodies around the world set a minimum threshold of 50% efficacy against symptomatic infection for the approval of any COVID-19 vaccine.

However, that has confused people into thinking that the authorities are taking shortcuts in giving us vaccines that barely work.

Come on – 50% efficacy? That’s like rolling the dice at the roulette table, right? That’s really NOT the case.

We prepared this table to show you how misleading efficacy rates are.

Recommended : Why COVID-19 Vaccine Efficacy Does NOT Matter!

COVID-19 Vaccine Protection Against
Symptomatic
Infection
Severe
Disease
Death
Pfizer Comirnaty 95.0% 100% 100%
Moderna mRNA-1273 94.1% 100% 100%
Gamaleya Sputnik V 91.6% 100% 100%
AstraZeneca AZD1222 76% ~ 85% 100% 100%
Novavax Covovax 60 ~ 89% 100% 100%
CanSino Convidecia 65.7% 90.98% 100%
Sinopharm BBIBP-CorV 79% ~ 86% 90% 100%
J&J Janssen COVID-19 66.0% 85% 100%
Sinovac CoronaVac 50.65% 83.7% 100%

The truth is all approved vaccines will protect you against severe disease, and prevent you from dying from COVID-19.

It would be really nice if you get a vaccine that protects you against even mild COVID-19, but not getting killed by it sounds pretty awesome to us!

Reason #3 : Vaccines Are In Limited Supply

COVID-19 vaccines are in limited supply, and there does not appear to be enough to vaccinate most countries until well into 2022.

Therefore, the possibility of vaccines being made available for private sale that you can pick and choose is remote, at least until 2022.

This is a pandemic – a global health crisis. The lives of trillions of people around the world come before your “right to choose”.

 

COVID-19 Vaccine : Don’t Choose. Get Yours ASAP!

It really does NOT matter which COVID-19 vaccine you get.

As long as it is an approved vaccine and you complete the dosing requirement, it will prevent you from getting severe COVID-19, or dying from it.

Instead of waiting for a particular COVID-19 vaccine, get the first one offered to you.

Don’t worry, when COVID-19 vaccines are available for sale, you can choose whichever vaccine you want and re-vaccinate yourself to your heart’s content!

 

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Chinese Vaccine Efficacy Not High? What Are The Facts?

Did Chinese CDC director, Gao Fu, admit that Chinese vaccine efficacy is “not high”?

Find out what’s the latest controversy surrounding Chinese vaccines, and what the FACTS really are!

 

Chinese CDC Director : Vaccine Efficacy Not High

On 10 April 2021, Gao Fu – the director of the Chinese Centres for Disease Control and Prevention – gave a talk on the Chinese COVID-19 vaccines at a conference in Chengdu, China.

He said that “the protection rates of existing vaccines are not high“, and suggested several options to improve their efficacy :

  • increasing the number of doses
  • adjusting the dosage
  • adjusting the interval between doses
  • mixing different vaccines

When that was picked up by International media, he told Chinese state media, Global Times, that his admission that Chinese vaccines had poor protection was “a complete misunderstanding“.

 

Chinese Vaccine Efficacy : The Current Facts

Now, let’s examine what we currently know about Chinese vaccine efficacy against COVID-19.

Fact #1 : Chinese Vaccines Are Mostly Comparable

Sinophiles and Chinese state media often claim that Chinese vaccines are superior, while Sinophobes insist that Chinese vaccines are junk.

The truth is – Chinese vaccines are far from the best, but are mostly comparable with Western vaccines that use older inactivated or viral vector technologies.

The outlier is CoronaVac from Sinovac Biologics, which barely made it past the 50% minimum efficacy line.

COVID-19 Vaccine Efficacy
Pfizer Comirnaty 95.0%
Moderna mRNA-1273 94.1%
Gamaleya Sputnik V 91.6%
Sinopharm BBIBP-CorV 79% ~ 86%
AstraZeneca AZD1222 76% ~ 85%
Novavax Covovax 60 ~ 89%
J&J Janssen COVID-19 66.0%
CanSino Convidecia 65.7%
Sinovac CoronaVac 50.65%

Fact #2 : Efficacy Blinds People To What’s Really Important

The public is obsessed over COVID-19 vaccine efficacy rates, but they are blind to what’s really important – protection against severe disease and death!

As this table shows, efficacy rates don’t tell the full story. The truth is that all these vaccines will protect you against severe disease, and prevent you from dying from COVID-19!

Even the worst Chinese vaccine in this table – the CoronaVac – has strong protection against severe disease, and completely protects against death!

Recommended : Why COVID-19 Vaccine Efficacy Does NOT Matter!

COVID-19 Vaccine Protection Against
Symptomatic
Infection
Severe
Disease
Death
Pfizer Comirnaty 95.0% 100% 100%
Moderna mRNA-1273 94.1% 100% 100%
Gamaleya Sputnik V 91.6% 100% 100%
AstraZeneca AZD1222 76% ~ 85% 100% 100%
Novavax Covovax 60 ~ 89% 100% 100%
CanSino Convidecia 65.7% 90.98% 100%
Sinopharm BBIBP-CorV 79% ~ 86% 90% 100%
J&J Janssen COVID-19 66.0% 85% 100%
Sinovac CoronaVac 50.65% 83.7% 100%

Fact #3 : Vaccine Efficacy Varies Against Virus Strains

All these COVID-19 vaccines are designed to target the original virus strain, whose genetic code was sequenced and released by Chinese scientists on 12 January 2020.

However, since then, the SARS-CoV-2 virus has spread globally and infected over 136 million people as of 12 April 2021.

Each infection represents an opportunity for the virus to mutate into new variants, some of which have changed behaviour or capability – creating a new strain.

Credit : The Conversation

Each new strain that develops has a chance to become more infectious, more lethal, and reduce the effectiveness of current vaccines.

That’s what Gao Fu is most likely referring to, and is a genuine concern for health authorities and vaccine manufacturers.

That’s why it is so important to quickly vaccinate people – so herd immunity can be achieved before a resistant strain develops!

Recommended : Which COVID-19 Vaccine Should YOU Choose?

Fact #4 : “Improved” Vaccines Are Being Developed

New strains may have new physical characteristics that allow them to evade the immune system of people vaccinated against the original strain.

So new, “improved” vaccines are being developed to target these new strains that are becoming more prevalent.

They are not actually “better” than current vaccines – they have just been modified to take into account the changes in the new strains.

What Gao Fu suggested in the conference are alternative methods to improving vaccine efficacy without developing an improved vaccine.

  • increasing the number of doses
  • adjusting the dosage
  • adjusting the interval between doses
  • mixing different vaccines

This would, arguably, allow for faster deployment since the Chinese can make use of their existing vaccines, and skip the development of an improved vaccine.

Such changes in vaccine protocol would, of course, require testing to establish their (improved) efficacy against the new variants / strains.

Fact #5 : Chinese Lack Of Transparency Is The Issue

The big problem with Chinese vaccines is not that they are less efficacious. The problem is that the Chinese have not been transparent about their vaccines.

Even though they were amongst the first to begin testing in 2020, they only released the RESULTS of their trials in press releases, refusing to release the actual data.

Only at the end of March 2021 did Sinopharm and Sinovac release data to the WHO Strategic Advisory Group of Experts (SAGE).

As of 12 April 2021, not a single Chinese manufacturer has publicly published the trial data for their vaccine.

All this eats into public confidence over Chinese vaccines. Why won’t any Chinese manufacturer release the trial data for their vaccine?

After all, all approved Western and Russian vaccines have publicly done so – Pfizer, Moderna, AstraZeneca, Johnson & Johnson and even Gamaleya.

 

Please Support My Work!

If you would like to support my work, you can do so via bank transfer /  PayPal / credit card.

Name : Adrian Wong

Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
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Thank you in advanced! 

 

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