Tag Archives: PAXLOVID

Did US Intentionally Release COVID Virus In Wuhan?!

Did the US government intentionally release the COVID-19 virus in Wuhan, to trigger a global pandemic so that people will accept vaccines?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : US Intentionally Released COVID Virus In Wuhan!

People are sharing an article by The Standard newspaper in Hong Kong, in which David Martin claimed that the US government intentionally released the COVID-19 virus in Wuhan, to trigger a global pandemic so that people will accept vaccines!

The article is being shared not only by anti-vaccination activists and conspiracy theorists, but also pro-CCP netizens and the Chinese 50 Cent Army (wumao, 五毛) as “evidence” that the COVID-19 pandemic was caused by the United States, and not China.

Here is an excerpt from the article. It’s long, so feel free to skip to the next section for the facts!

US ‘intentionally released Covid virus in Wuhan’ EU summit told

The Covid-19 coronavirus was “intentionally released” by the United States in Wuhan, China, with the target to trigger a global pandemic to raise public acceptance of vaccines, a US businessman specializing in patent auditing said.

David Martin, the founding chairman of M Cam asset management company, said at an International Covid Summit organized by the European Parliament in Brussels earlier this month that the US was responsible for the making of both coronaviruses causing the outbreaks of severe acute respiratory syndrome – or SARS – in 2003 and the Covid-19 pandemic in the past three years.

Recommended : Why International COVID Summit III Criticised Vaccine!

 

Truth : US Did Not Release COVID-19 Virus In Wuhan!

This appears to be yet another example of FAKE NEWS circulating on WhatsApp and social media platforms like TikTok and Twitter, and here are the reasons why!

Fact #1 : International COVID Summit III Was Not Organised By EU Parliament

The article wrongly states that the International COVID Summit III was organised by the European Parliament.

As I explained in my previous article, the International COVID Summit III was not an official EU Parliament event. It appears to be a private conference organised by COVID-19 conspiracy theorists and anti-vaccination activists.

Held in the Anna Lindh room of the European Parliament, it was not an official EU or European Parliament event, and only 5 MEPs attended as “co-hosting members” of the event.

In other words – the speakers at this event was only “testifying” to the few attendees in the room, and to the event’s livestream, not to the European Parliament.

You can read all about the ICS3 in my earlier article, Why International COVID Summit III Criticised Vaccine!

Fact #2 : This Was The First International COVID Summit

The article also wrongly called it the “third edition of the summit”. The first International COVID Summit, and International COVID Summit 2 do not appear to exist!

What actually existed were the Global COVID-19 Summit, and the 2nd Global COVID-19 Summit, but they are both completely unrelated to this International COVID Summit III. Those were official events involving heads of states and governments, as well as heads of international organisations, NGOs, and industries across the world.

So why would this International COVID Summit jump to its “third” iteration, when this was really the first time it was held? Could it be trying to mislead people into thinking that it was the third version of the Global COVID-19 Summit?!

Fact #3 : Coronavirus Was First Isolated In 1930s

David Martin said that the first coronavirus as a model of a pathogen was isolated in 1965. Well, I have no idea what he meant by “as a model of a pathogen”, but that’s wrong on several counts.

  • first coronavirus sample (IBV) was isolated in 1930s
  • second coronavirus sample (MHV) was isolated in 1947
  • third coronavirus sample (B814) was isolated in 1961
  • fourth coronavirus sample (229-E) was isolated in 1966
  • all four virus samples were determined to be from same group, and named “coronavirus” in 1967

You can read more about this in my earlier article – Did US + UK Create COVID-19 As Bioweapon?!

Fact #4 : Vaccines Work Even When Virus Mutates

All viruses can mutate when they replicate, just like how all animals evolve through reproduction. Just because a virus mutates does not mean that vaccines stop working.

Vaccines are training programs that teach our immune system how to identify the actual virus, and make its own antibodies against it. It’s like training your army by showing them how the enemy soldiers look like and behave, so they can train and prepare for war.

The vaccines do not stay in your body to fight the COVID-19 virus. They only teach your immune system how to do that, and they do that regardless of whether the virus has mutated or not.

As viruses evolve, they may get better at evading the antibodies that your immune system developed to defeat them. But that doesn’t mean they are immune. The antibodies may not be as effective, but they will still offer some protection, reducing the risk of severe disease and death.

This isn’t just theory. During the pandemic, the first vaccines only targeted the original SARS-CoV-2 virus. But it continued to offer robust protection against the Beta, Delta, and Omicron variants that came after.

Fact #5 : No Evidence US Released COVID-19 Virus In Wuhan

Claims that the US released the COVID-19 in Wuhan to create the pandemic has been circulating since 2020, but until today – there has been ZERO EVIDENCE of that.

Pro-CCP netizens and the Chinese 50 Cent Army (wumao, 五毛) accused US soldiers like Maatje Benassi of spreading the COVID-19 virus while participating in the 2019 Military World Games. They even spread a fake video (see below), claiming to show an American soldier spreading the COVID-19 virus in a subway in Wuhan.

However, all of those claims have long been proven to be completely false. More importantly, David Martin himself did not offer any actual evidence that the US released the COVID-19 virus, intentionally or otherwise, in Wuhan.

Recommended : Was COVID-19 Created In Fort Detrick Bio Lab?

Fact #6 : Most COVID-19 Vaccines Developed By Foreign Companies

The claim that the US government would create a pandemic to drive demand for vaccines is ludicrous. For one thing – big pharmaceutical companies are public-listed companies, and many are based outside of the United States.

More importantly – most COVID-19 vaccines were developed by foreign companies:

  • Only the Moderna Spikevax vaccine was developed in the United States
  • The Pfizer COMIRNATY vaccine was developed by German company, BioNTech
  • The AstraZeneca COVID-19 vaccine was developed by Oxford University, and AstraZeneca is a UK company.
  • The Johnson & Johnson COVID-19 vaccine was developed by Janssen Vaccines in the Netherlands.
  • The Sinovac, Sinopharm, CanSino COVID-19 vaccines were developed in China.

So the conspiracy theory that the United States created the COVID-19 pandemic for profit is absurd…

Fact #7 : Vaccines Are Cheaper Than Cures

I should also point out that prevention is always better and CHEAPER than the cure. Vaccines may seem expensive, and a way for Big Pharma to make billions of dollars. But vaccines are still better and CHEAPER than the cures.

Vaccines prevent you from developing severe COVID-19, thus negating your need to be hospitalised – which is expensive. Sure, Big Pharma now has drugs to treat COVID-19, like PAXLOVID, but they are much more expensive.

When it comes to dollars and common sense, vaccines are cheaper and better because they prevent hospitalisation. Big Pharma would make far more money selling you everything from expensive new drugs like PAXLOVID, or machines and drugs to keep you alive in the ICU!

Recommended : Do COVID-19 Vaccines DOUBLE Heart Attack Risk?!

Please help us FIGHT FAKE NEWS by sharing this fact check article out, and please SUPPORT our work!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact Check | ScienceTech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Jordon Trishton Walker on Directed Evolution : What are the Facts?

Jordon Trishton Walker has gone viral for claiming that Pfizer is thinking of mutating COVID-19 using Directed Evolution!

Take a look at the viral claims, and find out what the facts really are!

 

Jordon Trishton Walker : Pfizer is thinking of mutating COVID-19 using Directed Evolution!

Project Veritas recently released a “sting” video, in which they appeared to have entrapped Jordon Trishton Walker, who was identified as the Pfizer Director of Research and Development Strategic Operations and mRNA Scientific Planning.

In that viral video, Jordon (JTW) who was trying to impress his Tinder date – an undercover Project Veritas journalist (PV), claimed that Pfizer was thinking of mutating the COVID-19 virus using Directed Evolution.

When his Tinder date / undercover Project Veritas journalist suggested that it was Gain-of-Function, Jordon insisted that Directed Evolution was different from Gain-of-Function.

Here is a partial transcript from the video. For the full transcript, please see our earlier article.

PV : Pfizer ultimately is thinking about mutating COVID?

JTW : Well, that is not what we say to the public. No.
JTW : Don’t tell anyone this by the way, you have to promise you won’t tell anyone.
JTW : We’re exploring like – you know how the virus keeps mutating?
JTW : Well one of the things we’re exploring is like, why don’t we just mutate it ourselves so we could- we could create preemptively develop new vaccines, right? So we have to do that. If we’re gonna do that though, there’s a risk of like, as you could imagine, no one wants to be having a pharma company mutating fucking viruses.

PV : It [mutating COVID] sounds like Gain-of-Function to me.

JTW : I don’t know, it’s a little bit different. I think it’s different. It’s like, this, it’s definitely not Gain-of-Function.

PV : It sounds like it is, I mean, it’s okay.

JTW : No no no, but directed evolution is very different.
JTW : Well you’re not supposed to do Gain-of-Function research with the viruses.
JTW : They’d rather we not, but we do these selected structure mutations to try to see if we can make them more potent.

Read more : Did Project Veritas Show Pfizer Mutating COVID-19?!

 

Jordon Trishton Walker on Directed Evolution : What are the Facts?

Anti-vaccination activists are excitedly sharing the Project Veritas video of Jordon Trishton Walker as evidence that Pfizer was caught mutating the COVID-19 virus to develop new vaccines.

But the truth is – if you actually go through the Project Veritas video, it was really a nothingburger on Pfizer, and here are the reasons why…

Fact #1 : Project Veritas Is Infamous For Misinformation

Project Veritas is infamous for posting misinformation, and heavily edited videos that either cast a misleading angle on a story, or push misinformation.

In 2020, Project Veritas claimed that US Representative Ilhan Omar was linked to a “cash for ballots voter fraud scheme”, which turned out to be baseless.

In February 2021, Project Veritas posted a video of Mark Zuckerberg allegedly warning Facebook staff about the risks of mRNA vaccines, even though Zuckerberg changed his opinions three months earlier after asking Dr. Anthony Fauci to clarify the issue in a November 2020 livestream.

In October 2021, Project Veritas released a video of Pfizer scientist Nick Karl saying that natural immunity is better than vaccination, when in fact Nicholas Karl is a biochemist who was not involved in the development or manufacture of the Pfizer COVID-19 vaccine.

Fact #2 : His Job Does Not Involve Vaccine Development

While many people are obsessed in proving that Jordon Trishton Walker is really a Pfizer director of mRNA research, and not a consultant on loan / secondment from the Boston Consulting Group (BCG), it really does not matter.

Pfizer has a job position called Director, Research and Development and mRNA Scientific Strategy, which is close enough to the super-long title Jordon Trishton Walker is said to hold.

Ironically, that post is at the Pfizer Pearl River R&D facility near New York – the same place Nicholas Karl, the biochemist who got punked by Project Veritas in 2021 also worked at!

The job description, however, clearly shows that the director of R&D and mRNA Scientific Strategy is an office executive mainly dealing with business development.

Drive select projects within WRDM (Worldwide Research, Development and Medical) to deliver business critical insights to Pfizer leaders, such as the Executive Leadership Team, in partnership with internal and external stakeholders. These projects may include:

  • Leading select operational initiatives across Pfizer therapeutic areas, including delivering key aspects of the Corporate Strategic Plan and representing WRDM on corporate project teams.
  • Developing the strategic vision for mRNA technology at Pfizer and working cross-functionally with key stakeholders, such as Business Development, to enable decision-making on critical topics and ensure successful execution of the strategy. Identifying and prioritizing opportunities to deliver innovative medicines across Pfizer’s portfolio and advancing these priorities in collaboration with Pfizer’s Chief Scientific Officers and other WRDM leaders.
  • Maximizing the effectiveness of the President of WRDM on key internal and external deliverables.

Fact #3 : Jordon Walker Never Said Pfizer Was Mutating COVID-19 Virus

If you watch the Project Veritas video or read the transcript carefully, you will realise that Jordon Trishton Walker never said that Pfizer was mutating the COVID-19 virus. He only said that it was “a thought that came up” in one of the meetings.

… it was a thought that came up in a meeting and we were like, why do we not — it was like, we’re going to consider that with more discussions.

Fact #4 : Viruses Are Already Mutating Globally

It seems silly for Pfizer to intentionally infect monkeys to mutate the COVID-19 virus, to try and predict the next variant, when the virus is mutating rapidly globally – every infected person is literally a mutation factory!

Infecting monkeys also may not deliver the same variants as viruses that mutate in human beings, and may not serve as a good predictor of future variants.

Therefore, it would be much cheaper and certainly more accurate for Pfizer scientists to simply collect samples of new variants that are created every few months!

Fact #5 : Pfizer Modifying COVID-19 To Test PAXLOVID

Pfizer responded to the claims on January 27, 2023, stating that it has not conducted gain-of-function or directed evolution research when it came to the Pfizer-BioNTech COVID-19 vaccine (marketed as COMIRNATY).

However, Pfizer stated that it does modify the COVID-19 virus to produce the spike protein of the new variants identified by health authorities, to test whether its vaccine would continue to work against the new variants.

If any gain-of-function or directed evolution work was being done on the COVID-19 virus, Pfizer was only doing it to test if the virus can evade nirmatrelvir – the patented half of the PAXLOVID oral medication it developed.

Read more : Pfizer denies Gain of Function, Directed Evolution claims!

Fact #6 : Directed Evolution Cannot Predict Dominant Mutation

Directed evolution is a form of protein engineering that uses mutagenesis and the natural selection process to create proteins with desired characteristics.

While the mutagenesis process it uses can create many variants, directed evolution cannot predict which variants will end up becoming dominant.

That’s why it’s called directed evolution – the scientists direct the evolution of a gene to produce proteins they want, not predict what proteins will become “dominant”.

Jordon himself pointed out to the Project Veritas journalist that even if Pfizer tries mutating the virus, it may not predict future variants.

JTW : Yeah, if it works.

PV : What do you mean if it works?

JTW : Because some of the times there are mutations that pop up that we are not prepared for like the delta and omicron and things like that, so…

Fact #6 : mRNA Technology Allows For Quick Vaccine Development

In any case, it doesn’t make much sense for Pfizer to try and “predict” the next variant, because the mRNA technology allows for very quick vaccine development.

Moderna, for example, took only TWO DAYS to design its mRNA vaccine after Chinese scientists released the SARS-CoV-2 virus genome, and only 26 days to create its first batch of vaccines.

In other words – Pfizer, or rather BioNTech scientists, only need the genomic data of the latest variant to create a new vaccine. There is no real need to predict the next variant, because developing a new vaccine with mRNA technology is so quick!

Why mRNA vaccines take so long to get to market has more to do with testing and red tape, than actually creating them!

Please help us FIGHT FAKE NEWS by sharing this fact check article out, and please SUPPORT our work!

Don’t forget to protect yourself, and your family, by vaccinating against COVID-19!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact Check | HealthTech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Pfizer denies Gain of Function, Directed Evolution claim!

In response to the viral Project Veritas video, Pfizer has publicly denied conducting any Gain of Function, or Directed Evolution research in developing their COVID-19 vaccine!

Take a look at the viral claim, and find out what the facts really are!

Is Pfizer Mutating COVID-19 Virus Using Gain of Function / Directed Evolution?!

Project Veritas recently released a viral “sting” video involving Jordon Trishton Walker, who was identified as the Pfizer Director of Research and Development Strategic Operations and mRNA Scientific Planning.

In that viral video, short clips were edited to show Jordon Trishton Walker telling a Project Veritas journalist that Pfizer is mutating the COVID-19 virus to continue profiting from vaccines!

Project Veritas also edited their blurbs to make it sound like Jordon was admitting that the COVID-19 virus was created in Wuhan, China.

BREAKING: @Pfizer Exploring “Mutating” COVID-19 Virus For New Vaccines

“Don’t tell anyone this… There is a risk… have to be very controlled to make sure this virus you mutate doesn’t create something… the way that the virus started in Wuhan, to be honest”.

Recommended : Died Suddenly : Anti-Vaccination Movie Lies Exposed!

 

Pfizer Denies Gain of Function, Directed Evolution Claims!

At 8 PM on Friday, January 27, 2023, Pfizer issued a public statement to address the gain of function and directed evolution claims made in the Project Veritas video.

The statement did not address whether Jordon Trishton Walker is a Pfizer employee, or a consultant on secondment from the Boston Consulting Group.

Instead, the statement directly refutes the allegations that Pfizer conducted gain of function, or directed evolution research in developing its COVID-19 vaccine. Here is a quick summary of what Pfizer said:

Research Involving Pfizer-BioNTech COVID-19 Vaccine

  • Pfizer has not conducted gain of function research in the ongoing development of its COVID-19 vaccine.
  • Pfizer has not conducted directed evolution research in the ongoing development of its COVID-19 vaccine.
  • Working with partners (like BioNTech), Pfizer has modified the original SARS-CoV-2 virus so it produces the spike protein from new variants of concern that have been identified by public health authorities, to test their immune escape potential against antibodies produced by its COVID-19 vaccine antibodies.

This matches up with what Jordon Trishton Walker actually said in the viral Project Veritas video – Pfizer did not actually conduct any gain-of-function, or directed evolution research.

… it was a thought that came up in a meeting and we were like, why do we not — it was like, we’re going to consider that with more discussions.

Recommended : Did Study Show Pfizer Vaccine Altering Liver DNA In 6 Hours?!

Research Involving Pfizer PAXLOVID

  • Pfizer has also performed laboratory (in vitro) work to identify potential mutations that can cause resistance to nirmatrelvir – one of the two antiviral components in its PAXLOVID oral treatment for COVID-19.
  • Most of this work was conducted using computer simulations, or mutations of the main protease – an enzyme the virus uses to breaks down proteins.
  • However, Pfizer may engineer the SARS-CoV-2 virus to allow the assessment of antiviral activity in cells.
  • These in vitro resistance selection experiments are conducted in cells incubated with the SARS-CoV-2 virus and nirmatrelvir in a secure Biosafety Level 3 (BSL3) laboratory, to assess whether the main protease enzyme can mutate to become resistant to nirmatrelvir.

Pfizer appears to be admitting that it does engineer the COVID-19 virus, but clarifying that it was not done to create new vaccines. Rather, such research is being done to determine if PAXLOVID may potentially fail to work against a new variant.

Pfizer does not state whether they are engineering SARS-CoV-2 through gain-of-function or directed evolution, but such research is being conducted to determine whether the virus can mutate to become resistant to nirmatrelvir, which is the new protease inhibitor they developed.

However, as I pointed out in my earlier article, Pfizer does not actually need to perform such research to develop new COVID-19 vaccines using mRNA technology.

Read more : Did Project Veritas Show Pfizer Mutating COVID-19?!

 

Official Pfizer Statement On Gain of Function, Directed Evolution Claims

Here is the official Pfizer statement on the gain of function and directed evolution claims made in the Project Veritas video.

New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight.

In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required.

In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world.

Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease.

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact Check | HealthTech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Did Project Veritas Show Pfizer Mutating COVID-19?!

Did a viral Project Veritas video show that Pfizer is mutating the COVID-19 virus to create new vaccines through Directed Evolution?!

Take a look at the viral claim, and find out what the facts really are!

 

Project Veritas : Pfizer Mutating COVID-19 Virus For New Vaccines!

Project Veritas released another “sting” video involving Jordon Trishton Walker, who was identified as the Pfizer Director of Research and Development Strategic Operations and mRNA Scientific Planning.

In that viral video, short clips were edited to show Jordon (JTW) telling a Project Veritas journalist (PV) that Pfizer is mutating the COVID-19 virus to try and preemptively develop new vaccines.

Here is a transcript from the video, but it is very long as Project Veritas appeared to have been edited to repeat parts of the video. So please feel free to skip to the next section for the facts.

PV : Pfizer ultimately is thinking about mutating COVID?

JTW : Well, that is not what we say to the public. No.
JTW : Don’t tell anyone this by the way, you have to promise you won’t tell anyone.
JTW : We’re exploring like – you know how the virus keeps mutating?
JTW : Well one of the things we’re exploring is like, why don’t we just mutate it ourselves so we could- we could create preemptively develop new vaccines, right? So we have to do that. If we’re gonna do that though, there’s a risk of like, as you could imagine, no one wants to be having a pharma company mutating fucking viruses.
JTW : You have to be like very controlled to make sure that this virus that you mutate doesn’t create something like, you know, goes everywhere.
JTW : Which, I suspect is the way that the virus started in Wuhan, to be honest. Like, it makes no sense that this virus popped out of nowhere.

Read more : Jordon Trishton Walker on Directed Evolution : What are the Facts?

 

Project Veritas Did Not Show Pfizer Mutating COVID-19 Virus!

Anti-vaccination activists are excitedly sharing the Project Veritas video as evidence that Pfizer was caught mutating the COVID-19 virus to develop new vaccines.

But the truth is – if you actually go through the Project Veritas video, it was really a nothingburger on Pfizer, and here are the reasons why…

Fact #1 : Project Veritas Is Infamous For Misinformation

Project Veritas is infamous for posting misinformation, and heavily edited videos that either cast a misleading angle on a story, or push misinformation.

In 2020, Project Veritas claimed that US Representative Ilhan Omar was linked to a “cash for ballots voter fraud scheme”, which turned out to be baseless.

In February 2021, Project Veritas posted a video of Mark Zuckerberg allegedly warning Facebook staff about the risks of mRNA vaccines, even though Zuckerberg changed his opinions three months earlier after asking Dr. Anthony Fauci to clarify the issue in a November 2020 livestream.

In October 2021, Project Veritas released a video of Pfizer scientist Nick Karl saying that natural immunity is better than vaccination, when in fact Nicholas Karl is a biochemist who was not involved in the development or manufacture of the Pfizer COVID-19 vaccine.

Fact #2 : Pfizer mRNA Vaccine Created By BioNTech

What many people often forget is that the COMIRNATY mRNA vaccine was not created by Pfizer, but a German company called BioNTech, helmed by Uğur Şahin and Özlem Türeci – Germans of Turkish descent.

Pfizer is primarily the US manufacturing and testing partner for the BioNTech BNT162b2 vaccine, while in China, that would be Fosun Pharma.

Why this is important is because the bulk of the mRNA vaccine research work is done by BioNTech, not Pfizer or Fosun Pharma.

So it is unlikely that Jordon Trishton Walker would actually be involved in the development of any mRNA vaccine, even if he is the Pfizer Director of Research and Development Strategic Operations and mRNA Scientific Planning.

Recommended : Health Advocates Against Pfizer mRNA Vaccine : A Fact Check

Fact #3 : His Job Does Not Involve Vaccine Development

Pfizer has a job position called Director, Research and Development and mRNA Scientific Strategy, which is close enough to the super-long title Jordon Trishton Walker is said to hold.

Ironically, that post is at the Pfizer Pearl River R&D facility near New York – the same place Nicholas Karl, the biochemist who got punked by Project Veritas in 2021 also worked at!

The job description, however, clearly shows that the director of R&D and mRNA Scientific Strategy is an office executive mainly dealing with business development.

Drive select projects within WRDM (Worldwide Research, Development and Medical) to deliver business critical insights to Pfizer leaders, such as the Executive Leadership Team, in partnership with internal and external stakeholders. These projects may include:

  • Leading select operational initiatives across Pfizer therapeutic areas, including delivering key aspects of the Corporate Strategic Plan and representing WRDM on corporate project teams.
  • Developing the strategic vision for mRNA technology at Pfizer and working cross-functionally with key stakeholders, such as Business Development, to enable decision-making on critical topics and ensure successful execution of the strategy. Identifying and prioritizing opportunities to deliver innovative medicines across Pfizer’s portfolio and advancing these priorities in collaboration with Pfizer’s Chief Scientific Officers and other WRDM leaders.
  • Maximizing the effectiveness of the President of WRDM on key internal and external deliverables.

Fact #4 : Jordon Walker Never Said Pfizer Was Mutating COVID-19 Virus

If you watch the Project Veritas video or read the transcript above carefully, you will realise that Jordon Trishton Walker never said that Pfizer was mutating the COVID-19 virus. He only said that it was “a thought that came up” in one of the meetings.

… it was a thought that came up in a meeting and we were like, why do we not — it was like, we’re going to consider that with more discussions.

Read more : Pfizer denies Gain of Function, Directed Evolution claims!

Fact #5 : Viruses Are Already Mutating Globally

It seems silly for Pfizer to intentionally infect monkeys to mutate the COVID-19 virus, to try and predict the next variant, when the virus is mutating rapidly globally – every infected person is literally a mutation factory!

Infecting monkeys also may not deliver the same variants as viruses that mutate in human beings, and may not serve as a good predictor of future variants.

Therefore, it would be much cheaper and certainly more accurate for Pfizer scientists to simply collect samples of new variants that are created every few months!

Fact #6 : Directed Evolution Cannot Predict Dominant Mutation

Directed evolution is a form of protein engineering that uses mutagenesis and the natural selection process to create proteins with desired characteristics.

While the mutagenesis process it uses can create many variants, directed evolution cannot predict which variants will end up becoming dominant.

That’s why it’s called directed evolution – the scientists direct the evolution of a gene to produce proteins they want, not predict what proteins will become “dominant”.

Jordon himself pointed out to the Project Veritas journalist that even if Pfizer tries mutating the virus, it may not predict future variants.

JTW : Yeah, if it works.

PV : What do you mean if it works?

JTW : Because some of the times there are mutations that pop up that we are not prepared for like the delta and omicron and things like that, so…

Recommended : Did Study Show Pfizer Vaccine Altering Liver DNA In 6 Hours?!

Fact #7 : mRNA Technology Allows For Quick Vaccine Development

In any case, it doesn’t make much sense for Pfizer to try and “predict” the next variant, because the mRNA technology allows for very quick vaccine development.

Moderna, for example, took only TWO DAYS to design its mRNA vaccine after Chinese scientists released the SARS-CoV-2 virus genome, and only 26 days to create its first batch of vaccines.

In other words – Pfizer, or rather BioNTech scientists, only need the genomic data of the latest variant to create a new vaccine. There is no real need to predict the next variant, because developing a new vaccine with mRNA technology is so quick!

Why mRNA vaccines take so long to get to market has more to do with testing and red tape, than actually creating them!

Please help us FIGHT FAKE NEWS by sharing this fact check article out, and please SUPPORT our work!

Don’t forget to protect yourself, and your family, by vaccinating against COVID-19!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact Check | HealthTech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Is Lianhua Qingwen More Effective Than Paxlovid?!

Is the Chinese herbal medicine Lianhua Qingwen more effective than the Pfizer Paxlovid antiviral combination?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Lianhua Qingwen Is More Effective Than Paxlovid!

People are sharing a link to a Bloomberg called “Pfizer’s Covid Pill Doesn’t Work For Healthier Patients, Will Focus On Those With higher Risk”, together with this message :

Pfizer scams the world with US$22 billion in sales of Paxlovid to treat Covid.
Now finds that Paxlovid does not work and may cause rebound of disease.
Malaysia has ordered 200,000 doses at a cost of RM500 million –
RM2,500 per dose compared to a few bucks for China’s effective Lian Hwa pills.

 

Truth : Paxlovid Is More Effective Than Lianhua Qingwen!

This is yet another example of FAKE NEWS created by the Chinese 50 Cent Army (wumao, 五毛) as part of their campaign to support Traditional Chinese Medicine (TCM), and here are the reasons why…

Fact #1 : Paxlovid Is Combination Of Two Antiviral Drugs

Pfizer PAXLOVID is an antiviral treatment that consists of two protease inhibitors :

  • two 150 mg tablets of Nirmatrelvir (the new protease inhibitor developed by Pfizer)
  • one 100 mg tablet of Ritonavir (an old antiviral approved in 1996)

Protease inhibitors work by binding to proteolytic enzymes used by the SARS-CoV-2 virus to replicate. This prevents the virus from replicating in the infected cells, stopping the infection and preventing transmission.

Drug combinations like this offer a synergistic effect, above and beyond their individual abilities. In this combination, ritonavir helps to slow down the breakdown of nirmatrelvir, allowing it to remain in the body for a longer period at higher concentrations.

Fact #2 : Paxlovid Was Proven To Work Against COVID-19

Unlike Lianhua Qingwen, Paxlovid underwent and passed an actual randomised double-blind, placebo-controlled clinical trial.

In the EPIC-HR clinical trial, Paxlovid was shown to reduce hospitalisation or death from COVID-19 by 88%, compared to placebo.

That statistically significant result was why the US FDA issued an Emergency Use Authorisation (EUA) for Paxlovid on December 22, 2021.

The EUA allows Paxlovid to be used for the treatment of mild-to-moderate COVID-19 in adults and children 12 years and older, who are at high risk of developing severe COVID-19.

Read more : Did Cornell Name Ivermectin Most Effective Drug vs. Omicron?

Fact #3 : Paxlovid EPIC-HR Trial Involved High-Risk Patients

I should point out that the EPIC-HR trial involved adults who have a high risk of developing severe COVID-19 :

  • 18 years and older with a risk factor for developing severe COVID-19, or
  • 60 years and older, regardless of chronic medical conditions

All these patients also were not vaccinated against COVID-19, which puts them at higher risk of developing severe COVID-19.

Fact #4 : Paxlovid Not Effective In Normal Risk Patients

After successfully proving that Paxlovid worked for patients who are at high risk of developing severe COVID-19, Pfizer tested it on “standard risk patients”.

Their study showed a 51% relative risk reduction of developing severe COVID-19, which was not statistically significant.

That was why Pfizer halted further enrolment in its Paxlovid trial for “standard risk patients”, which are people who do not have co-morbidities – health conditions that put them at risk of developing severe COVID-19.

This “failure” actually shows the value of running clinical tests, before approving any drug. Unlike Paxlovid though, Lianhua Qingwen did not undergo any clinical trial to prove that it can treat or prevent COVID-19.

Fact #5 : Lianhua Qingwen Not Proven To Work Against COVID-19

Lianhua Qingwen (连花清瘟) has been heavily promoted by the Chinese government and the Chinese 50 Cent Army (wumao, 五毛), leading to massive sales in the global Chinese diaspora.

It then gained oversized importance when both Hong Kong and Shanghai distributed boxes of these capsules to help stave off the surge of COVID-19 in both cities.

Yet, the mass distribution of Lianhua Qingwen has done nothing to stop the spread of COVID-19 in both cities.

That’s because, unlike Paxlovid, there never was any evidence that Lianhua Qingwen can treat or prevent COVID-19.

Its main “call to fame” was a small Chinese study conducted early during the pandemic, which showed that it had only a modest effect on symptom recovery :

  • time to recover from fever : 2 days, instead of 3 days
  • time to recover from fatigue : 3 days, instead of 6 days
  • time to recover from coughing : 7 days, instead of 10 days

There was NO DIFFERENCE in the viral load, or the risk of developing severe COVID-19.

In other words – Lianhua Qingwen only helped to reduce symptoms, and was no different from taking over-the-counter drugs like paracetamol.

Read more : Did US NCBI Confirm Lianhua Qingwen Treats COVID-19?

Fact #6 : Lianhua Qingwen Should Not Be Taken To Prevent COVID-19

Official Chinese media outlets like CGTN and China Daily have falsely claimed that that Lianhua Qingwen was “proven effective for the treatment of COVID-19” and that it was “approved to treat [COVID-19] virus”.

However, Lianhua Qingwen cannot prevent COVID-19, and should not be taken on a long-term basis to prevent it, due to potential side effects.

The medicine could cause side effects such as nausea, vomiting, diarrhea and rash.

Fang Bangjiang, doctor from Long Hua Hospital of the Shanghai University of Traditional Chinese Medicine, said that Lianhua Qingwen has complex ingredients and is mainly suitable for COVID-19 patients with mild symptoms of fever and pneumonia but unsuitable for prevention.

Its ingredients will affect the renal system.

Fact #7 : Chinese Official Admits Lianhua Qingwen Cannot Kill Coronavirus

When Chinese Deputy Consul General in Vancouver, Kong Weiwei, was confronted about these claims, he said that people should be “mature enough” to do their own research and understand that Lianhua Qingwen cannot kill the COVID-19 virus :

They’re not babies. We don’t want to be like a nanny telling every one of them that these [Lianhua Qingwen capsules] cannot kill the virus.

Read more : Lianhua Qingwen Finally Tumbles Over Efficacy Concerns!

Fact #8 : Singapore HSA Warns Against Lianhua Qingwen Claims

The Singapore Health Sciences Authority (HSA) continues to warn the public not to believe the many misleading claims made about Lianhua Qingwen’s ability to treat or prevent COVID-19.

To date, there is no scientific evidence from randomised clinical trials to show that any herbal product, including Lianhua Qingwen products, can be used to prevent or treat COVID-19.

All herbal products formulated for common cold and flu, including CPM, should only be used to manage symptoms such as headache, runny or blocked nose, sore throat and cough.

We strongly advise members of the public not to fall prey to unsubstantiated claims or spread unfounded rumours that herbal products can be used to prevent or treat COVID-19.

Please help us FIGHT FAKE NEWS by sharing this fact check article out, and please SUPPORT our work!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact Check | Science | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Was Dr. Fauci Found Dead After Catching COVID-19?!

Was Dr. Anthony Fauci found dead in his home, after catching COVID-19?!

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Dr. Fauci Was Found Dead After Catching COVID-19!

Vancouver Times just posted a story claiming that Dr. Anthony Fauci was found dead in his home, after catching COVID-19!

Dr. Fauci has been found dead in his home after he caught Covid-19. The head of the government’s Covid response had four doses of the vaccine, making his death suspicious. Doctors haven’t ruled out that the vaccines may have contributed to his death.

Fauci was isolating and recovering at home from a case of Covid-19, at first reporting “mild” symptoms. His symptoms suddenly took a turn for the worst, and Fauci was found dead by his wife, who promptly called for paramedics. However, the paramedics arrived too late to save Fauci.

Fauci’s response to the Covid pandemic was seen as “heavy handed.” Many people had called for his resignation, even murder. Steve Bannon suggested on his podcast that Fauci should be decapitated. He was subsequently banned from Twitter and YouTube.

The mainstream media and big tech want to hide the truth. Beat them at their own game by sharing this article!

 

Truth : Dr. Fauci Was NOT Found Dead After Catching COVID-19!

This is yet another example of FAKE NEWS created to generate page views and money from gullible people.

Fact #1 : Vancouver Times Is A Fake News Website

Vancouver Times is a “content aggregator” (copy and paste) website that is known for creating fake news to generate more page views and money.

To look legitimate, they copy and paste news from legitimate news organisations. To drive traffic, they create fake news, sometimes masked as “satire”.

To give themselves a veneer of deniability, they label themselves as a “satire website” in their About Us section.

Vancouver Times is the most trusted source for satire on the West Coast. We write satirical stories about issues that affect conservatives.

Here are some of their fake news that we debunked :

Fact #2 : Dr. Anthony Fauci Only Has Mild COVID-19 Symptoms

Dr. Anthony Fauci tested positive for COVID-19 using a rapid antigen test on June 15, 2022.

After his diagnosis, he isolated himself, and started working from his home, following CDC guidelines for COVID-19. He is currently experiencing only mild symptoms.

Fact #3 : Dr. Anthony Fauci Just Testified At Senate Hearing

Dr. Anthony Fauci was healthy and well, when he sparred with Senator Rand Paul at the Senate HELP hearing on the US federal pandemic response on June 16, 2022.

Together with CDC Director Rochelle Walensky, and FDA Commissioner Robert Califf, he answered questions from other Senators at the hearing which lasted over 2.5 hours.

Fact #4 : Dr. Anthony Fauci Received Four COVID-19 Vaccine Doses

Dr. Fauci was fully-vaccinated, with two booster doses of the COVID-19 vaccine. He is also taking the Pfizer antiviral drug, Paxlovid, as a precaution.

If the COVID-19 vaccine can kill people, as Vancouver Times suggested, Dr. Fauci would have been struck dead by any of the four doses he received.

Fact #5 : COVID-19 Vaccines Are Safe + Effective

Even though Dr. Fauci is 81 years old, the odds of him dying from COVID-19 is extremely remote, because he is not only fully-vaccinated, he was boosted twice.

Because his body’s own immune system has been trained to tackle COVID-19, he will most likely experience mild symptoms that will not become worsen, much less kill him.

Despite what anti-vaccination activists may claim, COVID-19 vaccines have proven to be both safe and effective in preventing severe infections and deaths.

The RECoVaM study, for example, showed that the vast majority of people who died from COVID-19 were either unvaccinated, or partially vaccinated.

Read more : RECoVaM Study Highlights How Well Covid-19 Vaccines Work!

Fact #6 : There Is No Such Thing As A Publication Ban

If Dr. Anthony Fauci was found dead in his home, it would have been worldwide news, even if he didn’t recently test positive for COVID-19.

Vancouver Times likes to use the “media blackout” claim, to explain why you can’t find any reputable media outlet reporting on Dr. Fauci’s purported death from COVID-19 or the vaccine.

That’s utter and complete bullshit. No one – not a judge, not even the FBI – can control the worldwide media, or prevent anyone from writing about such a momentous arrest.

You can also be sure that even if the mainstream media refused to run the story, it would have been gleefully published by bloggers and anti-vaccination websites.

Yet, not a single press / gonzo outlet published their account of this incredible story? That’s because IT NEVER HAPPENED…

Read more : Did US Special Forces Just Arrest Dr. Anthony Fauci?!

Fact #7 : Mainstream Media + Big Tech Would Have Loved The Hype

Vancouver Times is gaslighting you about how mainstream media and Big Tech want to hide the “truth” about Dr. Fauci’s death.

They would all loved it if Dr. Fauci was really found dead in his home. The news would have driven tons of traffic and engagement to their websites / platforms.

In fact, that was precisely why Vancouver Times created the fake story – to drive traffic, for the ad money.

Everything that Vancouver Times publishes should be regarded as FAKE NEWS, until proven otherwise.

Please help us fight fake news websites like Vancouver Times – SHARE this fact check out, and SUPPORT our work!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Fact CheckScienceTech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Malaysia Approves Pfizer PAXLOVID Antivirals For COVID-19!

Malaysia just approved the Pfizer PAXLOVID antiviral treatment for COVID-19!

Here is what you need to know!

 

Malaysia Approves Pfizer PAXLOVID Antivirals For COVID-19!

On 3 March 2022, the Malaysia Health Ministry (KKM) announced that the 370th Drug Control Authority meeting has agreed to give conditional approval to:

PAXLOVID (PF-07321332 150mg Film-Coated Tablets and Ritonavir 100mg Film-Coated Tablets)

Registrant : Pfizer (Malaysia) Sdn. Bhd.
Manufacturer : Pfizer Manufacturing Deutschland GmbH, Germany and Pfizer Ireland Pharmaceuticals, Ireland
Indication : COVID-19 treatment for adults age 18 years and above who do not require oxygen therapy, and are high-risk for severe COVID-19.

The Health Ministry warns that PAXLOVID is not meant to replace COVID-19 vaccination and public health measures.

 

Pfizer PAXLOVID : What Is It?

Pfizer PAXLOVID is an antiviral treatment that consists of two protease inhibitors :

  • two 150 mg tablets of Nirmatrelvir (the new protease inhibitor developed by Pfizer)
  • one 100 mg tablet of Ritonavir (an old antiviral approved in 1996)

Protease inhibitors work by binding to proteolytic enzymes used by the SARS-CoV-2 virus to replicate. This prevents the virus from replicating in the infected cells, stopping the infection and preventing transmission.

Drug combinations like this offer a synergistic effect, above and beyond their individual abilities. In this combination, ritonavir helps to slow down the breakdown of nirmatrelvir, allowing it to remain in the body for a longer period at higher concentrations.

Read more : Did Cornell Name Ivermectin Most Effective Drug vs. Omicron?

PAXLOVID was first given an Emergency Use Authorisation (EUA) by the US FDA on 22 December 2021, for the treatment of mild to moderate COVID-19 in adults and children 12 years and older.

It is meant to be taken by those who are at high-risk of developing severe COVID-19, and must be taken within 5 days of symptom onset. In addition, PAXLOVID must not be taken for more than 5 consecutive days.

The EPIC-HR trial showed that PAXLOVID is able to reduce the risk of hospitalisation or death from COVID-19 b y 88%, compared to placebo.

Individuals who took PAXLOVID have reported side effects like impaired sense of taste, diarrhoea, high blood pressure and muscle aches.

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Health | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!

Did Cornell Name Ivermectin Most Effective Drug vs. Omicron?

Did Cornell University just confirm ivermectin as the most effective drug against the Omicron variant of COVID-19?

Take a look at the viral claim, and find out what the facts really are!

 

Claim : Cornell Calls Ivermectin Most Effective Drug vs. Omicron!

Antivaxxers and alternative medicine websites like Mercola are sharing what they claim to be a Cornell University study that names ivermectin as the most effective drug against the Omicron variant.

Here is an example of a WhatsApp message that people are sharing about this Cornell University study.

It’s a long post, so feel free to skip to the next section for the facts.

14.2.2022

LATEST STUDY BY CORNELL UNIVERSITY USA FOUND IVERMECTIN MORE EFFECTIVE AGAINST OMICRON THAN OTHER DRUGS, INCLUDING PFIZER’S EXPENSIVE PAXLOVID

Researchers used a computational analysis to look at the Omicron variant, which has demonstrated a lower clinical presentation and lower hospital admission rates.

After having retrieved the complete genome sequence and collecting 30 variants from the database, the researchers analyzed 10 drugs against the virus, including:

 

Truth : Cornell Did Not Call Ivermectin Most Effective Drug vs. Omicron!

This is yet another example of ivermectin FAKE NEWS, created by antivaxxers and alternative health websites like Mercola.

Let me show you just how they maliciously lied to you about this study…

Fact #1 : Study Was Not Conducted By Cornell University

The study in question is called Insights from a computational analysis of the SARS-CoV-2 Omicron variant: Host-pathogen interaction, pathogenicity and possible therapeutics.

The study was conducted by Parvez et. al. – a team from the Kyoto University Graduate School of Medicine in Japan, and the Shahjalal University of Science & Technology in Bangladesh.

This study on ivermectin and other protease inhibiting drugs has NOTHING to do with Cornell University.

Fact #2 : arXiv Is An Online Library Managed By Cornell University

The study summary in arXiv has a Cornell University logo at the top, which the fake news creator hopes will convince you that the study was done by a Cornell University team.

The truth is – arXiv is an open access repository (library) of scientific papers that is financed and managed by the Cornell University Library. Hence, the Cornell University logo.

That does not mean that the papers submitted to arXiv were conducted or endorsed by Cornell University.

Fact #3 : arXiv Papers Are NOT Peer-Reviewed

The C19Ivermectin website claims that the Parvez et. al. paper has been peer-reviewed. That’s false.

arXiv stores scientific preprints and post-prints (also called e-prints) that any scientist choose to submit.

All papers submitted to arXiv are NOT peer-reviewed, and must NOT be used without proper context.

While papers are typically peer-reviewed before becoming post-print and published (see graphic below), this is not the case for arXiv.

In fact, arXiv specifically warns that their post-prints are NOT peer-reviewed at the top of the page :

Important: e-prints posted on arXiv are not peer-reviewed by arXiv; they should not be relied upon without context to guide clinical practice or health-related behavior and should not be reported in news media as established information without consulting multiple experts in the field.

Fact #4 : Study Used Computer Modelling

The Parvez et. al. study (PDF download) was not conducted in the real world, or even in a laboratory. It was conducted on a computer.

They used computational analysis to analyse the binding potential for ten drugs that target the SARS-CoV-2’s protease protein.

However, this was all done on a computer, and may not necessarily reflect real world results. They must be reviewed (to look for mistakes), and then confirmed in actual lab and real world tests.

As the study authors themselves state, “While these hypotheses hold great value and may provide significant insights into the therapeutic strategies, further research is crucial to authenticate these statements.

Fact #5 : PAXLOVID Consists Of Two Drugs, Not One

The Parvez et. al. paper looked at individual drugs, and labelled Nirmatrelvir as PAXLOVID.

That is incorrect, as PAXLOVID is a combination of two protease inhibitors :

  • two 150 mg tablets of Nirmatrelvir (the new protease inhibitor developed by Pfizer)
  • one 100 mg tablet of Ritonavir (an old antiviral approved in 1996)

Drug combinations like this offer a synergistic effect, above and beyond their individual abilities.

Hence, the Parvez et. al. study does not accurately reflect the ability of the PAXLOVID combination of Nirmatrelvir and Ritonavir to simultaneously and synergistically bind to the coronavirus protease enzyme.

And no – you cannot combine or average their results. It doesn’t work that way…

Pro Tip : If you are searching for Ritonavir in the Parvez et. al. study, do note that they wrongly called it Ritonvir.

Fact #6 : In Silico Results Are Least Clinically Important

Computational analysis can help scientists identify potential drug candidates, but the results are not always clinically important.

In this study’s case, it looked at the affinity (ease) at which ten drugs can bind to the protease enzyme of the SARS-CoV-2 virus.

While that is a critical feature of protease inhibiting drugs that block the coronavirus’ ability to replicate, it does not tell us other important things like :

  • the minimum drug plasma level to inhibit replication
  • maximum dose a human being can safely tolerate
  • the dose required to achieve the therapeutic plasma level
  • drug interactions and adverse effects
  • plasma half life and drug metabolism

In the order of clinical importance, such computational (in silico) research is the least significant. That’s why we cannot draw any conclusions from such studies.

Fact #7 : PAXLOVID Proven To Work Against COVID-19

Like many people, I am aghast at the high price of the Pfizer PAXLOVID drug combination. However, low cost is not a requirement for FDA approval.

The US FDA issued PAXLOVID an Emergency Use Authorisation (PDF download) because its Phase 2/3 trial results (PDF download) showed an 88% reduction in the risk of hospitalisation or death from COVID-19.

Even so, the US FDA limited PAXLOVID’s use to only treat early cases of mild-to-moderate COVID-19 :

  • Not authorised for severe or critical COVID-19
  • Not authorised as a preventive measure (prophylaxis) against COVID-19
  • Cannot be used for longer than 5 consecutive days

Fact #8 : Ivermectin Not Proven To Work Clinically Against COVID-19

Ivermectin has shown promise against the COVID-19 virus in laboratory tests since April 2020, but that has not translated into actual clinical benefit.

In other words – scientists can only show that ivermectin kills the coronavirus in laboratory tests, but not in actual human beings.

Here is a meta-analysis of ivermectin RCTs (randomised control trials), with three fraudulent studies removed – Elgazzar, Okomus and Niaee. Results towards the left suggest a clinical benefit for ivermectin.

Taken in totality, the latest meta-analysis show that the clinical effect of ivermectin on COVID-19 patients is NOT SIGNIFICANT enough to warrant its use as a treatment.

While it is ridiculous that Pfizer would charge so much for PAXLOVID, there is fortunately a low-cost way to prevent COVID-19 – vaccines.

Getting vaccinated is a cheap way to avoid getting COVID-19, and avoid the use of expensive drugs like PAXLOVID.

If you want to stick it to Pfizer, get vaccinated against COVID-19!

 

Please Support My Work!

Support my work through a bank transfer /  PayPal / credit card!

Name : Adrian Wong
Bank Transfer : CIMB 7064555917 (Swift Code : CIBBMYKL)
Credit Card / Paypal : https://paypal.me/techarp

Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

He continues to devote countless hours every day writing about tech, medicine and science, in his pursuit of facts in a post-truth world.

 

Recommended Reading

Go Back To > Health | Fact Check | Tech ARP

 

Support Tech ARP!

Please support us by visiting our sponsors, participating in the Tech ARP Forums, or donating to our fund. Thank you!